Dr. Eric Anslyn

Dr. Eric Anslyn is University Distinguished Teaching Professor and Welch Regents Chair in the Department of Chemistry at The University of Texas at Austin. In 2018, Anslyn was selected by the Howard Hughes Medical Institute to be an HHMI professor. Prior to joining the University of Texas, Anslyn completed postdoctoral work at Columbia University in New York. He has authored more than 300 scientific articles and filed more than 50 patents. Anslyn is a cofounder of Erisyon, Inc.

Academic Appointment(s)

  • University Distinguished Teaching Professor and Welch Regents Chair, Department of Chemistry, The University of Texas at Austin

Educational Background

  • California State University, Northridge: B.S. Chemistry (1982)
  • California Institute of Technology: Ph.D., Chemistry (1987)
  • Columbia University: Postdoctoral Fellow, Chemistry (1987 – 1989)

Recent Publications

  • “Synthesis of Carboxy ATTO 647N Using Redox Cycling for Xanthone Access” Bachman, J.L.; Pavlich, C.I.; Boley, A.J.; Marcotte, E.M.; Anslyn, E.V. Org. Lett. 2020, 22, 381-385.
  • “Regineering a Reversible Covalent-Bonding Assembly to Optically Detect ee in b-Chiral Primary Alcohols” Matthew, M.; Featherson, A.L.; Choi, S.; King, S.; Miller, S.J.; Anslyn, E.V. Chem, 2019, 5, 3196-3206.
  • “2-Amino-3’-dialkylaminobiphenyl-base fluorescent intracellular probes for nitric oxide surrogate N 2 O 3 ” Escamilla, P.R.; Shen, Y.; Zhang, Q.; Hernandez, D.S.; Howard, C.J.; Qian, X.; Filonov, D.Y.; Kinev, A.V.; Shear, J.B.; Anslyn, E.V.; Yang, Y. Chem. Sci. 2019, in press.
  • “Quantification of ERK kinase activity in biological sampels using differential sensing” Zamora-Olivares, D,; Kaoud, T.; Zeng, L.; Pridgen, J.R.; Zhuang, D.; Ekpo, Y.E.; Nye, J.R.; Telles, M.; Anslyn, E.V.; Dalby, K. ACS Chem Biol 2019, In press
  • “Modulating multi-functional ERK complexes by covalent targeting of a recruitiment site in vivo” Kaoud, T.S.; Johnson, W.H.; Ebelt, N.D.; Pieserchio, A.; Zamora-Olivares, D.; Van Ravenstein, S.X.; Pridgen, J.R.; Edupuganti, R.; Sammons, R.; Cano, M.; Anslyn, E.V.; Dalby, K. Nat. Comm. 2019, 10, 1-15.
  • “Expanding the limits of the second genetic code with ribozymes” Lee, J.; Schwieter, K.E.; Watkins, A.M.; Kim, D.S.; Yu, H.; Schwarz, K.J.; Lim, H.; Coronado, J.; Byrom, M.; Anslyn, E.V.; Ellington, A.D.; Moore, J.; Jewett, M. Nat. Comm. 2019, 10, 1-12.
  • “Design of Chiral Supramolecular Polymers Exhibiting a Negative Nonlinear Response” Chen, X.X.; Lin, X.- Y.; Wu, X.; Gale, P.A.; Anslyn, E.V.; Jiang, Y.-B. J. Org. Chem. 2019, 84, 14587-14592.
  • “Mechanistic studies of a “Declick” reaction” Meadows, M.K.; Sun, X.; Kolesnichenko, I.V.; Hinson, C.M.; Johnson, K.A. Chem. Sci. 2019, 10, 8817-8824.
  • “The Mechanisms of Boronate Ester Formation and Fluorescent Turn-On in Ortho-aminomethylphenylboronic Acids” Sun X; Chapin BM; Metola P; Collins B; Wang B; James TD; Anslyn EV, Nat. Chem. 2019, 11(9), 768-778, DOI: doi: 10.1038/s41557-019-0314-x.
  • “Rapid Optical Determination of Enantiomeric Excess, Diastereomeric Excess, and Total Concentration Using Dynamic-Covalent Assemblies: A Demonstration Using 2-Aminocyclohexanol and Chemometrics” Herrera BT; Moor SR; McVeigh M; Roesner EK; Marini F; Anslyn EV, J. Am. Chem. Soc., 2019, 141(28), 11151-11160, DOI: 10.1021/jacs.9b03844

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